This qualitative study uses human ecology theory, continuity theory, and loss theory to consider the domains of loss experienced by Southeast Asian elders who have resettled in Minneapolis/St. Paul. Forty extensive life history narratives (five men and five women in each of four cultural groups: Cambodian, Hmong, Laotian, and Vietnamese) were analyzed for loss domains using life history methods. Four domains of loss were identified: loss of a way of life, loss of key relationships, role loss and fears about the loss of cultural heritage and cultural transmission to younger generations. An ecological spiral model is proposed as one way to understand how Southeast Asian elders experience family life. In the final chapter, the implications of this study for theory and for the practice of family life education are examined.